Anaconda (Python distribution)

Anaconda (Python distribution)

Anaconda is an open source data science and artificial intelligence distribution platform for the Python programming language. Developed by Anaconda, Inc., an American company founded in 2012, the platform is used to develop and manage data science and AI projects. In 2024, Anaconda Inc. has about 300 employees and 45 million users. == History == Co-founded in Austin, Texas in 2012 as Continuum Analytics by Peter Wang and Travis Oliphant, Anaconda Inc. operates from the United States and Europe. Anaconda Inc. developed Conda, a cross-platform, language-agnostic binary package manager. It also launched PyData community workshops and the Jupyter Cloud Notebook service (Wakari.io). In 2013, it received funding from DARPA. In 2015, the company had two million users including 200 of the Fortune 500 companies and raised $24 million in a Series A funding round led by General Catalyst and BuildGroup. Anaconda secured an additional $30 million in funding in 2021. Continuum Analytics rebranded as Anaconda in 2017. That year, it announced the release of Anaconda Enterprise 5, an integration with Microsoft Azure, and had over 13 million users by year's end. In 2022, it released Anaconda Business; new integrations with Snowflake and others; and the open-source PyScript. It also acquired PythonAnywhere, while Anaconda's user base exceeded 30 million in 2022. In 2023, Anaconda released Python in Excel, a new integration with Microsoft Excel, and launched PyScript.com. The company made a series of investments in AI during 2024. That February, Anaconda partnered with IBM to import its repository of Python packages into Watsonx, IBM's generative AI platform. The same year, Anaconda joined IBM's AI Alliance and released an integration with Teradata and Lenovo. In 2024, Anaconda's user base reached 45 million users and Barry Libert was named company CEO, after serving on Anaconda's board of directors. He was succeeded as CEO in October 2025 by David DeSanto, who also became a company director. In May 2025, the company introduced the first unified AI platform for Open Source, Anaconda AI Platform, a central control for AI workflows that enables customization in Python-based enterprise AI development. That July, after reaching over $150 million in a Series C funding round, Anaconda was evaluated at about $1.5 billion. == Overview == Anaconda distribution comes with over 300 packages automatically installed, and over 7,500 additional open-source packages can be installed from the Anaconda repository as well as the Conda package and virtual environment manager. It also includes a GUI, Anaconda Navigator, as a graphical alternative to the command-line interface (CLI). Conda was developed to address dependency conflicts native to the pip package manager, which would automatically install any dependent Python packages without checking for conflicts with previously installed packages (until its version 20.3, which later implemented consistent dependency resolution). The Conda package manager's historical differentiation analyzed and resolved these installation conflicts. Anaconda is a distribution of the Python programming language (and previously also R) for scientific computing (data science, machine learning applications, large-scale data processing, predictive analytics, etc.), that aims to simplify package management and deployment. Anaconda distribution includes data-science packages suitable for Windows, Linux, and macOS. Other company products include Anaconda Free, and subscription-based Starter, Business and Enterprise. Anaconda's business tier offers Package Security Manager. Package versions in Anaconda are managed by the package management system Conda, which was spun out as a separate open-source package as useful both independently and for applications other than Python. There is also a small, bootstrap version of Anaconda called Miniconda, which includes only Conda, Python, the packages they depend on, and a small number of other packages. Open source packages can be individually installed from the Anaconda repository, Anaconda Cloud (anaconda.org), or the user's own private repository or mirror, using the conda install command. Anaconda, Inc. compiles and builds the packages available in the Anaconda repository itself, and provides binaries for Windows 32/64 bit, Linux 64 bit and MacOS 64-bit (Intel, Apple Silicon). Anything available on PyPI may be installed into a Conda environment using pip, and Conda will keep track of what it has installed and what pip has installed. Custom packages can be made using the conda build command, and can be shared with others by uploading them to Anaconda Cloud, PyPI or other repositories. The default installation of Anaconda2 includes Python 2.7 and Anaconda3 includes Python 3.7. However, it is possible to create new environments that include any version of Python packaged with Conda. === Anaconda Navigator === Anaconda Navigator is a desktop graphical user interface (GUI) included in Anaconda distribution that allows users to launch applications and manage Conda packages, environments and channels without using command-line commands. Navigator can search for packages on Anaconda Cloud or in a local Anaconda Repository, install them in an environment, run the packages and update them. It is available for Windows, macOS and Linux. The following applications are available by default in Navigator: JupyterLab Jupyter Notebook QtConsole Spyder Glue Orange RStudio Visual Studio Code === Conda === Conda is an open source, cross-platform, language-agnostic package manager and environment management system that installs, runs, and updates packages and their dependencies. It was created for Python programs, but it can package and distribute software for any language, including multi-language projects. The Conda package and environment manager is included in all versions of Anaconda, Miniconda, and Anaconda Repository. == Anaconda.org == Anaconda Cloud is a package management service by Anaconda where users can find, access, store and share public and private notebooks, environments, and Conda and PyPI packages. Cloud hosts useful Python packages, notebooks and environments for a wide variety of applications. Users do not need to log in or to have a Cloud account, to search for public packages, download and install them. Users can build new Conda packages using Conda-build and then use the Anaconda Client CLI to upload packages to Anaconda.org. Notebooks users can be aided with writing and debugging code with Anaconda's AI Assistant.

Systems development life cycle

The systems development life cycle (SDLC) describes the typical phases and progression between phases during the development of a computer-based system. These phases progress from inception to retirement. At base, there is just one life cycle, but the taxonomy used to describe it may vary; the cycle may be classified into different numbers of phases and various names may be used for those phases. The SDLC is analogous to the life cycle of a living organism from its birth to its death. In particular, the SDLC varies by system in much the same way that each living organism has a unique path through its life. The SDLC does not prescribe how engineers should go about their work to move the system through its life cycle. Prescriptive techniques are referred to using various terms such as methodology, model, framework, and formal process. Other terms are used for the same concept as SDLC, including software development life cycle (also SDLC), application development life cycle (ADLC), and system design life cycle (also SDLC). These other terms focus on a different scope of development and are associated with different prescriptive techniques, but are about the same essential life cycle. The term "life cycle" is often written without a space, as "lifecycle", with the former more popular in the past and in non-engineering contexts. The acronym SDLC was coined when the longer form was more popular and has remained associated with the expansion, even though the shorter form is popular in engineering. Also, SDLC is relatively unique as opposed to the TLA SDL, which is highly overloaded. == Phases == Depending on the source, the SDLC is described as having different phases and using different terms. Even so, there are common aspects. The following attempts to describe notable phases using notable terminology. The phases are somewhat ordered by the natural sequence of development, although they can be overlapping and iterative. === Conceptualization === During conceptualization (a.k.a. conceptual design, system investigation, feasibility), options and priorities are considered. A feasibility study can determine whether the development effort is worthwhile via activities such as understanding user needs, cost estimation, benefit analysis, and resource analysis. A study should address operational, financial, technical, human factors, and legal/political concerns. === Requirements analysis === Requirements analysis (a.k.a. preliminary design) involves understanding the problem and determining what is needed. Often this involves engaging users to define the requirements and recording them in a document known as a requirements specification. === Design === During the design phase (a.k.a. detail design), a solution is planned. The plan can include relatively high-level information such as describing the major components of the system. The plan can include relatively low-level information such as describing functions, screen layout, business rules, and process flow. The design phase is informed by the requirements of the system. The design must satisfy each requirement. The design may be recorded in textual documents as well as functional hierarchy diagrams, example screen images, business rules, process diagrams, pseudo-code, and data models. === Construction === During construction (a.k.a. implementation, production), the system is realized. Based on the design, hardware and software components are created and integrated. This phase includes testing sub-components, components and the integration of some components, but typically does not include testing at the complete system level. This phase may include the development of training materials, including user manuals and help files. === Acceptance === The acceptance phase (a.k.a. system testing) is about testing the complete system to ensure that it meets customer expectations (requirements). === Deployment === The deployment phase (a.k.a. implementation) involves the logistics of delivery to the customer. Some systems are deployed as a single instance (i.e. in the cloud), and deployment may be ad hoc and manual. Some systems are built in quantity and are associated with manufacturing process and commissioning. This phase may include training users to use the system. It may include transitioning future development to support staff. === Maintenance === During the maintenance phase (a.k.a. operation, utilization, support) development is largely inactive, although this phase does include customer support for resolving user issues and recording suggestions for improvement. Fixes and enhancements are handled by returning to the first phase, conceptualization. For minor changes, the cycle may be significantly abbreviated compared to initial development. === Decommission === Decommission (a.k.a. disposition, retirement, phase-out) is when the system is removed from use, i.e., when it reaches end-of-life. == Practices == === Management and control === SDLC phase objectives are described in this section with key deliverables, a description of recommended tasks, and a summary of related control objectives for effective management. It is critical for the project manager to establish and monitor control objectives while executing projects. Control objectives are clear statements of the desired result or purpose and should be defined and monitored throughout a project. Control objectives can be grouped into major categories (domains), and relate to the SDLC phases as shown in the figure. To manage and control a substantial SDLC initiative, a work breakdown structure (WBS) captures and schedules the work. The WBS and all programmatic material should be kept in the "project description" section of the project notebook. The project manager chooses a WBS format that best describes the project. The diagram shows that coverage spans numerous phases of the SDLC, but the associated MCD (Management Control Domains) shows mappings to SDLC phases. For example, Analysis and Design is primarily performed as part of the Acquisition and Implementation Domain, and System Build and Prototype is primarily performed as part of delivery and support. === Work breakdown structured organization === The upper section of the WBS provides an overview of the project scope and timeline. It should also summarize the major phases and milestones. The middle section is based on the SDLC phases. WBS elements consist of milestones and tasks to be completed rather than activities to be undertaken, and have a deadline. Each task has a measurable output (e.g., an analysis document). A WBS task may rely on one or more activities (e.g., coding). Parts of the project needing support from contractors should have a statement of work (SOW). The development of an SOW does not occur during a specific phase of SDLC but is developed to include the work from the SDLC process that may be conducted by contractors. === Baselines === Baselines are established after four of the five phases of the SDLC, and are critical to the iterative nature of the model. Baselines become milestones. functional baseline: established after the conceptual design phase. allocated baseline: established after the preliminary design phase. product baseline: established after the detailed design and development phase. updated product baseline: established after the production construction phase. In the following diagram, these stages are divided into ten steps, from definition to creation and modification of IT work products:

Artificial intelligence in pharmacy

Artificial intelligence in pharmacy refers to the application of artificial intelligence (AI) techniques across pharmaceutical research and practice, including drug discovery, drug delivery, safety monitoring, clinical decision support, and pharmacy operations. Machine learning, deep learning, and natural language processing have been applied to tasks ranging from molecular design to patient adherence monitoring, with the aim of reducing development costs, improving accuracy, and personalizing treatment. Adoption has been uneven. Barriers include limited AI training among pharmacists, high infrastructure costs, and the risk of harm from models trained on unrepresentative data. Regulatory frameworks for AI-based pharmaceutical tools remain in active development across most jurisdictions. == Applications == === Drug discovery and development === Drug development is resource-intensive: bringing a single drug to market typically costs around $2.6 billion and takes 12–14 years. Machine learning algorithms have been applied to analyze molecular datasets to identify potential drug candidates, predict drug–target interactions, and optimize formulations. Artificial neural networks and generative adversarial networks have been used in drug discovery tasks including virtual screening, structure-activity relationship modeling, and de novo molecule generation. Peptides designed using AI methods have shown activity against multidrug-resistant bacteria, and transcriptomic data from human cell lines has been used to train deep learning models to classify drugs by therapeutic properties. Results in drug discovery have been mixed. AI models depend on the quality and diversity of their training data; those trained on narrow chemical libraries can fail to generalize to novel molecular scaffolds. The gap between high virtual screening hit rates and success in preclinical or clinical testing remains a persistent challenge, and the translation of computationally predicted candidates into approved drugs has been slower than early projections suggested. === Drug delivery systems === AI methods including neural networks, principal component analysis, and neuro-fuzzy logic have been applied to identifying biological targets for pharmaceuticals and analyzing genetic information relevant to drug design. Computational models can predict how a formulation will behave in biological systems, helping narrow the field before laboratory synthesis begins. Systems have been proposed that monitor patient response and adjust doses in real time based on individual physiology, with potential applications in chronic disease management. Research has also explored AI applications in targeted cancer treatments and oral vaccine delivery, areas where precise control over drug release kinetics is a design priority. === Drug safety === AI has been applied to predicting and detecting adverse drug reactions using techniques including knowledge graphs, logistic regression classifiers, and neural networks. A 2023 study developed a machine learning algorithm using knowledge graph analysis to classify known causes of adverse reactions. Natural language processing and deep learning models including long short-term memory (LSTM) networks have shown better performance than conventional methods for detecting opioid misuse, drawing on both structured data from electronic health records and unstructured sources such as clinical notes. AI-based pharmacovigilance systems can scan large volumes of electronic health records and social media for drug safety signals at a scale not feasible with manual review. Limitations include difficulty distinguishing drug-related adverse events from unrelated conditions in free-text data, and the need for validated benchmarks to measure model performance against existing safety monitoring standards. === Clinical decision support and personalized medicine === Machine learning systems trained on patient datasets can predict individual risk profiles, including potential allergies and drug–drug interactions, reducing the risk of harm in complex polypharmacy cases where the number of possible interactions exceeds what a clinician can readily assess. Personalized dosing models have been developed for drugs with narrow therapeutic windows — including anticoagulants and immunosuppressants — using patient-specific variables such as weight, renal function, and relevant genetic markers. Prospective clinical validation of these systems has lagged behind their technical development. Most published evaluations report performance on retrospective datasets, and the regulatory pathway for AI-based clinical decision support tools in pharmacy varies by jurisdiction. === Pharmacy operations and automation === Robotic and AI-driven systems have been applied to dispensing accuracy and pharmacy logistics. At the UCSF Medical Center, robotic technology produced 350,000 medication doses with no dispensing errors recorded. Robots such as TUG assist with preparing and transporting medications and laboratory samples within hospital settings. AI has also been applied to inventory management, with demand-forecasting systems predicting medicine requirements to reduce shortages and minimize waste from expired stock. In community pharmacy settings, AI tools have been used to flag potential prescription errors and alert pharmacists to drug–drug interactions before dispensing. === Medication adherence === Confirming that patients take prescribed medications as directed is a persistent challenge in healthcare. AI-enabled tools including smart pillboxes, RFID tags, ingestible sensors, and video check-ins have been applied to this problem. Smart pillboxes record when they are opened, providing real-time adherence data that can be reviewed remotely by care teams. Ingestible sensors transmit a signal after dissolution, offering direct confirmation of ingestion rather than proxy measures such as pill count or self-report. == Adoption challenges == === Barriers === Several barriers limit AI adoption in pharmacy practice. Many published evaluations report model performance on retrospective datasets rather than prospective clinical outcomes, making it difficult to assess real-world benefit. Pharmacists have reported limited AI training and knowledge, and research facilities often lack the computational infrastructure required for model development and validation. Models trained on biased or unrepresentative datasets can produce misleading results with direct patient safety consequences. === Regulatory frameworks === Regulatory frameworks for AI-based pharmaceutical tools are in active development. In the United States, the Food and Drug Administration (FDA) has issued guidance on AI and machine learning-based software as a medical device, addressing requirements for pre-market review and post-market performance monitoring. The European Medicines Agency has published discussion papers on the use of AI across the medicines development lifecycle, with particular attention to transparency in model training and validation. The absence of harmonized international standards creates compliance complexity for developers operating across multiple jurisdictions. === Ethical challenges === AI adoption raises data privacy and security concerns, including the risk of exposing sensitive patient information through data breaches. Algorithmic bias presents a related hazard: a model trained on an unrepresentative patient population may generate unsuitable treatment recommendations for patients not reflected in its training data, with potential for disparate outcomes across demographic groups. The opacity of some machine learning models, particularly deep neural networks, limits clinicians' ability to interpret or contest a recommendation, raising questions of accountability when a model-assisted decision results in patient harm. === Proposed solutions === Responses proposed in the literature include AI-focused education programs for pharmacists, increased public funding for healthcare AI research, encryption and governance frameworks for patient data, and regulatory requirements to prevent the use of biased training datasets. Greater transparency about training data provenance, model architecture, and validation methodology has also been recommended, including disclosure requirements in regulatory submissions. === Future directions === Research groups have called for tighter integration between AI systems and electronic health records to reduce healthcare costs and improve continuity of care across settings. International collaboration through shared AI frameworks and federated learning approaches has been proposed to address data scarcity in underrepresented patient populations and accelerate validation across institutions.

Perry Rhodan

Perry Rhodan is a German space opera franchise, named after its hero. It commenced in 1961 and has been ongoing for decades, written by an ever-changing team of authors. Having sold approximately two billion copies (in novella format) worldwide (including over one billion in Germany alone), it is the most successful science fiction book series ever written. The first billion of worldwide sales was celebrated in 1986. The series has spun off into comic books, audio dramas, video games and the like. A reboot, Perry Rhodan NEO, was launched in 2011 and began publication in English in April 2021. == Print publication == The series has spun off into many different forms of media, but originated as a serial novella published weekly since 8 September 1961 in the Romanheft (Meaning "Magazine novel") format. These are digest-sized booklets, usually containing 66 pages, the German equivalent of the now-defunct (and generally longer) American pulp magazine. They are published by Pabel-Moewig Verlag, a subsidiary of Bauer Media Group headquartered in Hamburg. As of February 2019, 3000 booklet novels of the original series, 850 spinoff novels of the sister series Atlan and over 400 paperbacks and 200 hardcover editions have been published, totalling over 300,000 pages. == English translation == The first 126 novels (plus five novels of the spinoff series Atlan) were translated into English and published by Ace Books between 1969 and 1978, with the same translations used for the British edition published by Futura Publications which issued only 39 novels. When Ace cancelled its translation of the series, translator Wendayne Ackerman self-published the following 19 novels (under the business name 'Master Publications') and made them available by subscription only. Financial disputes with the German publishers led to the cancellation of the American translation in 1979. An attempt to revive the series in English was made in 1997–1998 by Vector Publications of the US, which published translations of four issues (1800–1803) from the current storyline being published in Germany at the time. The series and its spin-offs have captured a substantial fraction of the original German science fiction output and exert influence on many German writers in the field. == Structure == The series is told in an arc storyline structure. An arc—called a "cycle"—would have anywhere from 25 to 100 issues devoted to it. Similar subsequent cycles are referred to as a "grand-cycle". == History == ‘Perry Rhodan, der Erbe des Universums’ (Eng: ‘The Heir to the Universe’, though the American/British editions instead used the subtitle 'Peacelord of the Universe') was created by German science fiction authors K. H. Scheer and Walter Ernsting and launched in 1961 by German publishing house Arthur Moewig Verlag (now Pabel-Moewig Verlag). Originally planned as a 30 to 50 volume series, it has been published continuously every week since, celebrating the 3000th issue in 2019. Written by an ever-changing team of authors, many of whom, however, remained with the series for decades or life, Perry Rhodan is issued in weekly novella-size installments in the traditional German Heftroman (pulp booklet) format. Unlike most German Heftromane, Perry Rhodan consists not of unconnected novels but is a series with a continuous, increasingly complex plotline, with frequent back references to events. In addition to its original Heftroman form, the series now also appears in hardcovers, paperbacks, e-books, comics and audiobooks. Over the decades there have also been comic strips, numerous collectibles, several encyclopedias, audio plays, inspired music, etc. The series has seen partial translations into several languages. It also spawned the German-Italian-Spanish 1967 movie Mission Stardust, which is widely considered so terrible that many fans of the series pretend it never existed. Coinciding with the 50th-anniversary World Con, on 30 September 2011, a new series named Perry Rhodan Neo began publication, attracting new readers with a reboot of the story, starting in the year 2036 instead of 1971, and a related but independent story-line. On 2 April 2021, light novel and manga publisher J-Novel Club announced Perry Rhodan NEO as a launch title for its new J-Novel Pulp imprint, making this the first ongoing English release of new Perry Rhodan serials in over 20 years. It has become the most popular science fiction book series of all time. == Overview == === Fictional history === The story begins in 1971. During the first human Moon landing by US Space Force Major Perry Rhodan and his crew, they discover a marooned extraterrestrial space ship from the fictional planet Arkon, located in the (real) M13 cluster. Appropriating the Arkonide technology, they proceed to unify Terra and carve out a place for humanity in the galaxy and the cosmos. Two of the accomplishments that enable them to do so are positronic brains and starship drives for near-instantaneous hyperspatial translation. These were directly borrowed from Isaac Asimov's science fiction. As the series progresses, major characters, including the title character, are granted relative immortality. They are immune to age and disease, but not to violent death. The story continues over the course of millennia and includes flashbacks thousands and even millions of years into the past. The scope widens to encompass other galaxies, even more remote regions of space, parallel universes and cosmic structures, time travel, paranormal powers, a variety of aliens ranging from threatening to endearing, and bodiless entities, some of which have godlike powers. === Multiverse === The universe in which the main plot generally takes place is called the Einstein Universe (or "Meekorah"). Its laws are for the most part identical to those of the real universe, as known by late 20th century science. Newer theories about dark matter and dark energy are currently not used in the series. The laws of nature follow old theories that have been disproven, in order to protect series continuity. There are many other universes, each to a greater or lesser extent different from the familiar one, in which, for example one in which time runs slower, an anti-matter universe, a shrinking universe, etc. Each universe possesses its owntimelines, which are for the most part unreachable from each other but may be accessed by special means, thereby itself creating many more parallel timelines. The Einstein Universe is embedded in a high-dimensional manifold, called Hyperspace. This hyperspace consists of several subspaces use for faster-than-light travel by technological means. The exact traits of those higher dimensions are got yhr mode pity unexplained. The border of the universe is a dimension called the deep, once used for construction of the gigantic disc-shaped world Deepland. === Psionic Web and Moral Code === The Psionic Web crosses the whole universe, constantly emitting "vital energy" and "psionic energy", guaranteeing normal (organic among others) life and the wellbeing of higher entities. The Moral Code crosses through all universes, and is linked to the Psionic Web. It is subdivided into the Cosmogenes, which are again subdivided into the Cosmonucleotids. The Cosmonucleotids determine reality and fate for their respective parts of a given universe, via messengers. Higher beings are trying to gain control of this Code to rule reality. The Moral Code itself was not installed by the higher beings, the higher powers by themselves have no clue why or by whom the Code was made. Once the Cosmocrats ordered Perry Rhodan to find the answer to the third ultimate question: "Who initiated the LAW and what does it accomplish?" Perry Rhodan had the chance to receive the answer at the mountain of creation, but refused, as he knew that the answer would destroy his mind. The negative Superintelligence Koltoroc had received the answer to the last ultimate question, 69 million years BC at Negane Mountain, but it is not known if it made any use of the information. === Onion-shell model === An evolutionary schema, similar to the Great Chain of Being, called the "onion-shell model" is employed in relationship to all life. Here, continuous evolution is from lower to higher lifeforms, culminating in bodiless entities. Later in the series, further lifeforms, representing stages between the known shells, were introduced. The main shells are: Lifeless matter Bacteria Higher animals Intelligent species Intelligent species that have contacted other species Superintelligences (SI) Matter sources/ Matter sinks Cosmocrats / Chaotarchs (High Powers) Powers close to the "Horizon of the LAW", the essence of the Multiverse The Superintelligences are the next step above normal minds. They can be born, for example, when a species collectively gives up its bodies and unites their spirits. Such Superintelligences may claim as their domain areas consisting of up to several galaxies (the entity known as "E

A Fire Upon the Deep

A Fire Upon the Deep is a 1992 science fiction novel by American writer Vernor Vinge. It is a space opera involving superhuman intelligences, aliens, variable physics, space battles, love, betrayal, genocide, and a communication medium resembling Usenet. A Fire Upon the Deep won the Hugo Award in 1993, sharing it with Doomsday Book by Connie Willis. Besides the normal print book editions, the novel was also included on a CD-ROM sold by ClariNet Communications along with the other nominees for the 1993 Hugo awards. The CD-ROM edition included numerous annotations by Vinge on his thoughts and intentions about different parts of the book, and was later released as a standalone e-book. It has a loose prequel, A Deepness in the Sky, from 1999, and a direct sequel, The Children of the Sky, from 2012. == Setting == The novel is set in various locations within the Milky Way. The galaxy is divided into four concentric volumes called the "Zones of Thought"; it is not clear to the novel's characters whether this is a natural phenomenon or an artificially created one. Each Zone has fundamental differences in basic physical laws. One of the main consequences of these differences is the effect on intelligence. Artificial intelligence and automation is most directly affected, in that advanced hardware and software from the Beyond or the Transcend will work less and less well as a ship descends towards the Unthinking Depths. Biological intelligence is affected to a lesser degree. The four zones are spoken of in terms of "low" to "high" as follows: The Unthinking Depths are the innermost zone, surrounding the Galactic Center. In it, only minimal forms of intelligence, biological or otherwise, are possible. This means that any ship straying into the Depths will be stranded, effectively permanently. Even if the crew did not die immediately—and some forms of life native to "higher" Zones would likely do so—they would be rendered incapable of even human intelligence, leaving them unable to operate their ship in any meaningful way. Surrounding the Depths is the Slow Zone or Slowness. "Old Earth" is in this Zone, although Earth plays no significant role in the story. Biological intelligence is possible in "the Slowness", but not true, sentient, artificial intelligence. Faster than light travel (FTL) is impossible in the Slow Zone. Faster-than-light communication is impossible into or out of the Slow Zone. As the boundaries of the Zones are subject to change, accidental entry into the Slow Zone is a major hazard at the "Bottom" of the Beyond. Starships which operate near the Beyond/Slow Zone border often have an auxiliary Bussard ramjet drive, so that if they accidentally stray into the Slow Zone, they will at least have a backup (sub-light) drive to try to reach the Beyond. Such ships also tend to include "coldsleep" equipment, as it is likely that any such return will still take many lifetimes for most species. The next layer outward is the Beyond, within which artificial intelligence, FTL travel, and FTL communication are possible. All human civilizations in the Beyond are descended from a single ethnic Norwegian group. The original settlement of this group is known as Nyjora; other human settlements in the Beyond include Straumli Realm and Sjandra Kei. In the Beyond, FTL travel is accomplished by making many small "jumps" across space, with the efficiency of the drive increasing the farther a ship travels from the galactic core. The Beyond is not a homogeneous zone; it includes the "High Beyond", "Middle Beyond", and the "Bottom of the Beyond", depending on distance from the galactic core. The Beyond is populated by a very large number of interstellar and intergalactic civilizations which are linked by an FTL communication network, "the Net", sometimes cynically called the "Net of a Million Lies". The Net is depicted as working much like the Usenet network in the early 1990s, with transcripts of messages containing header and footer information as one would find in such forums. The outermost layer, containing the galactic halo, is the Transcend, within which incomprehensible, superintelligent beings dwell. When a "Beyonder" civilization reaches the point of technological singularity, it can "Transcend", becoming a "Power". Such Powers always seem to relocate to the Transcend, seemingly necessarily, where they become engaged in activities which are entirely mysterious to those in the Beyond. == Plot == An expedition from Straumli Realm, a human civilization in the High Beyond, investigates a newly discovered data archive in the Low Transcend. The expedition's facility, High Lab, is gradually compromised by a superintelligence that is accidentally awoken by the researchers. This superintelligence is later known as the Blight. Shortly before the Blight's final "flowering", two self-aware entities, created similarly to the Blight, plot to aid the humans before the Blight can gain its full powers. Finally recognizing their danger, the High Lab researchers attempt to flee in two ships. The Blight destroys one ship; a second ship, carrying many High Lab children in coldsleep boxes, escapes. This ship lands on a distant planet at the Bottom of the Beyond. The planet is occupied by dog-like creatures, dubbed "Tines", who live in packs as group minds. The Tines have a level of technology comparable to the human Middle Ages. Upon landing, however, the two surviving adults, Arne and Sjana Olnsdot, are ambushed and killed by Tine fanatics known as Flenserists, in whose realm they have landed. The Flenserists capture their children, Jefri and Johanna. Johanna is rescued by a Tine named Peregrine and taken to a neighboring kingdom ruled by Woodcarver. A distress signal from the Straumli ship eventually reaches Relay, a major information provider for the Net. A Transcendent being named "Old One" contacts Relay, seeking information about the Blight and the humans who released it. Old One then reconstitutes a human man named Pham Nuwen from the wreckage of a spaceship to act as its agent. Pham remains unsure if he is a construct or if his memories are real. Ravna Bergsndot, the only human Relay employee, traces the Straumli ship's signal to the Tines' world and persuades her employer to investigate. Ravna contracts the merchant vessel Out of Band II to transport her and Pham. The ship is owned by two Skroderiders, Blueshell and Greenstalk. Before the mission is launched, the Blight launches a surprise attack on Relay and kills Old One. As Old One dies, it downloads its anti-Blight information into Pham. Pham, Ravna and the Skroderiders barely escape Relay's destruction in the Out of Band II. During their journey to Tine's World, Ravna communicates with Jefri. Jefri is manipulated to believe that Woodcarver is his enemy. The Flenserist leaders, Steel and Tyrathect, use Ravna's information to develop advanced technology such as cannon and radio communication. Meanwhile, Johanna and the knowledge stored in her dataset device help Woodcarver rapidly develop as well. The Blight expands, taking over several civilizations, brainwashing their populations, and seizing archives in the Beyond. On the Net, some claim that humans are the means by which the Blight is able to spread. Anti-human fanatics destroy the entire civilization of Sjandra Kei, which is Ravna's home world. The Out of Band II is pursued by three fleets: anti-human fanatics, survivors from Sjandra Kei, and a shadow fleet controlled by the Blight. During the pursuit, Ravna and Pham learn that every member of the Skroderider species can be subverted by the Blight; this drives a wedge between the crew members. Ships from Sjandra Kei sacrifice themselves to delay the Blight and the anti-human ships, allowing the Out of Band II to reach Tine's World before the Blight. When the Out of Band II arrives at Tine's World, the humans ally with Woodcarver to defeat the Flenserists and rescue Jefri. Blueshell sacrifices himself to rescue Jefri. Pham then initiates an anti-Blight Countermeasure, which was aboard the humans' ship. The Countermeasure extends the Slow Zone outward by thousands of light years. This envelops and destroys the Blight, but results in the destruction of thousands of civilizations and trillions of deaths. The humans are stranded on the Tines' World, now in the depths of the Slow Zone. Activating the Countermeasure proves fatal to Pham, but before he dies, the remnant of Old One reveals to him that, although his body is a reconstruction, his memories are indeed real. == Related works == Vinge first used the concepts of "Zones of Thought" in a 1988 novella The Blabber, which occurs after Fire. Vinge's novel A Deepness in the Sky (1999) is a prequel to A Fire Upon the Deep set 20,000 years earlier and featuring Pham Nuwen. Vinge's The Children of the Sky, "a near-term sequel to A Fire Upon the Deep", set ten years later, was released in October 2011. Vinge's former wife, Joan D. Vinge, has also written s

Perceptual robotics

Perceptual robotics is an interdisciplinary science linking Robotics and Neuroscience. It investigates biologically motivated robot control strategies, concentrating on perceptual rather than cognitive processes and thereby sides with J. J. Gibson's view against the Poverty of the stimulus theory. As a working definition, the following quote from Chapter 64 by H. Bülthoff, C. Wallraven and M. Giese from The Springer Handbook of Robotics, edited by Bruno Siciliano and Oussama Khatib, published by Springer in 2007, could be used: In the following we will apply the term Perceptual Robotics to signify the design of robots based on principles that are derived from human perception on all three levels in the sense of Marr. This includes a realization in terms of specific neural circuits as well as the transfer of more abstract biologically-inspired strategies for the solution of relevant computational problems.

Taylor Swift deepfake pornography controversy

In late January 2024, sexually explicit AI-generated deepfake images of American musician Taylor Swift were proliferated on social media platforms 4chan and X (formerly Twitter). Several artificial images of Swift of a sexual or violent nature were quickly spread, with one post reported to have been seen over 47 million times before its eventual removal. The images led Microsoft to enhance Microsoft Designer's text-to-image model to prevent future abuse. Moreover, these images prompted responses from anti-sexual assault advocacy groups, US politicians, Swifties, and Microsoft CEO Satya Nadella, among others, and it has been suggested that Swift's influence could result in new legislation regarding the creation of deepfake pornography. A similar controversy emerged in August 2025, when The Verge reported AI image and video tool Grok Imagine generated sexually explicit images and videos of Swift from an otherwise innocuous text prompt. == Background == American musician Taylor Swift has been the target of misogyny and slut-shaming throughout her career. American technology corporation Microsoft offers AI image creators called Microsoft Designer and Bing Image Creator, which employ censorship safeguards to prevent users from generating unsafe or objectionable content. Members of a Telegram group discussed ways to circumvent these censors to create pornographic images of celebrities. Graphika, a disinformation research firm, traced the creation of the images back to a 4chan community. == Reactions == For some, the deepfake images of Swift immediately became a source of controversy and outrage. Other internet users found them humorous and absurd, such as the image making it appear as though Swift was to engage in sexual intercourse with Oscar the Grouch. The images drew condemnations from Rape, Abuse & Incest National Network and SAG-AFTRA. The latter group, who had been following issues regarding AI-generated media prior to Swift's involvement, considered the images "upsetting, harmful and deeply concerning." Microsoft CEO Satya Nadella, whose company's products were believed to be used to make these images, responded to the controversy as "alarming and terrible", further stating his belief that "we all benefit when the online world is a safe world." === Taylor Swift === A source close to Swift told the Daily Mail that she would be considering legal action, saying, "Whether or not legal action will be taken is being decided, but there is one thing that is clear: These fake AI-generated images are abusive, offensive, exploitative, and done without Taylor's consent and/or knowledge." === Politicians === White House press secretary Karine Jean-Pierre expressed concern over the counterfeit images, deeming them "alarming", and emphasized the obligation of social media platforms to curb the dissemination of misinformation. Several members of American politics called for legislation against AI-generated pornography. Later in the month, a bipartisan bill was introduced by US senators Dick Durbin, Lindsey Graham, Amy Klobuchar and Josh Hawley. The bill would allow victims to sue individuals who produced or possessed "digital forgeries" with intent to distribute, or those who received the material knowing it was made without consent. The European Union struck a deal in February 2024 on a similar bill that would criminalize deepfake pornography, as well as online harassment and revenge porn, by mid-2027. === Social media platforms === X responded to the sharing of these images on their own website with claims they would suspend accounts that participated in their spread. Despite this, the photos continued to be reshared among accounts of X, and spread to other platforms including Instagram and Reddit. X enforces a "synthetic and manipulated media policy", which has been criticized for its efficacy. They briefly blocked searches of Swift's name on January 27, 2024, reinstating them two days later. === Swifties === Fans of Taylor Swift, known as Swifties, responded to the circulation of these images by pushing the hashtag #ProtectTaylorSwift to trend on X. They also flooded other hashtags related to the images with more positive images and videos of her live performances. == Cultural significance == Deepfake pornography has remained highly controversial and has affected figures from other celebrities to ordinary people, most of whom are women. Journalists have opined that the involvement of a prominent public figure such as Swift in the dissemination of AI-generated pornography could bring public awareness and political reform to the issue.